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Deletion of the ferrochelatase gene in a patient with protoporphyria. Blood. 2013 Jun; 45(6):450-9. 1990 Jan; 85(1):248-55. The renin-angiotensin-aldosterone system in cerebral small vessel disease. 1991; 10(3-4):452-5. Studies with human cultured skin fibroblasts. Sancho-Bru P, Bataller R, Colmenero J, Gasull X, Moreno M, Arroyo V. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. 1998 May; 114(5):1035-45. Glutamine metabolism stimulates intestinal cell MAPKs by a cAMP-inhibitable, Raf-independent mechanism. 2021 09; 191(9):1564-1579. 1989 Sep; 30(9):1220-4. 1998 Jun; 42(6):779-87. 1994 Jul 29; 269(30):19203-6. Westwick JK, Fleckenstein J, Yin M, Yang SQ, Bradham CA. 2000 Dec; 279(6):G1333-42. 1994 Oct 21; 269(42):26396-401. M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway. Lang A, Schrum LW, Schoonhoven R, Tuvia S, Sols-Herruzo JA. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Am J Physiol. 2001 Jul 01; 167(1):173-80. People who share similar concepts with this person. University of California San Diego named John M. Carethers as the vice chancellor for Health Sciences (VCHS), effective January 1, 2023. 2000 Aug; 119(2):446-60. Nature. 2013 Jul; 145(1):16-31. 1999 Mar; 15(2):103-7. Activated hepatic stellate cells and portal fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice. Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal. His career has been replete with accomplishments in research, clinical work and administration, and at UCSD he is still able to round on patients, Korean J Hepatol. J Biol Chem. 2009 Jan 16; 378(3):348-53. Proc Am Thorac Soc. Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis. 2000 Jan; 48(1):39-44. Interleukin-6 increases rat metalloproteinase-13 gene expression through stimulation of activator protein 1 transcription factor in cultured fibroblasts. 2012; 7(4):e34218. Hum Gene Ther. Schwabe RF, Bradham CA, Uehara T, Hatano E, Bennett BL, Schoonhoven R. p18(INK4c) collaborates with other CDK-inhibitory proteins in the regenerating liver. The future of gastroenterology and gastroenterology. The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis. 2006 Apr; 290(4):G583-9. Dig Dis. Hepatology. J Cell Biol. Development of exchange lists for Mediterranean and Healthy Eating diets: implementation in an intervention trial. Taura K, Miura K, Iwaisako K, Osterreicher CH, Kodama Y, Penz-Osterreicher M. Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats. Nat Commun. AIDS. 2022 Apr 04. Biotechniques. N Engl J Med. The recombination and integration of DNAs introduced into mouse L cells. Differential expression of human lysyl hydroxylase genes, lysine hydroxylation, and cross-linking of type I collagen during osteoblastic differentiation in vitro. 2008 Dec; 48(6):2016-26. J Hepatol. Fra, Fra away: the complex role of activator protein 1 in liver injury. Am J Physiol Gastrointest Liver Physiol. 2009 Nov; 58(11):1517-27. Cardiovascular health of nonagenarians in southern Italy: a cross-sectional, home-based pilot study of longevity. Brenner succeeds Kristiina Vuori, M.D., Ph.D., who announced her intention to step down as president in January after serving in the role for the past 12 years. 2009 Oct; 297(4):G726-34. Gastroenterology. 1994 Sep; 3(9):1695-7. Hepatology. Techniques to measure nucleic acid-protein binding and specificity. J Biol Chem. Hellerbrand C, Jobin C, Iimuro Y, Licato L, Sartor RB. Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice. 1999; 8(3):151-63. Hepatology. Alteration of interferon-a/ receptors in chronic hepatitis B patients. 2020; 2(2):fcaa133. 2020 05; 158(6):1728-1744.e14. Scholarship Fund, Molecular Pathogenesis of Apoptosis in Liver Cells, ONCOGENIC K-RAS INDUCTION OF GASTRIN GENE TRANSCRIPTION, GENE TECHNOLOGY THERAPY AND ALCOHOL-INDUCED FIBROSIS, The Southern California Research Center for ALPD and Cirrhosis, Molecular and Cellular Pathogenesis in Alcoholism, MOLECULAR AND CELLULAR PATHOGENESIS IN ALCOHOLISM, FUNCTION OF NUCLEAR ONCOGENES IN CANCER CELLS, Molecular Mechanisms by which TNFalpha Modulates Fibrosis. 2010; 2010:362847. Serum ?-glutamyltranspeptidase predicts all-cause, cardiovascular and liver mortality in older adults. Analysis of the collagen alpha 1(I) promoter. Proc Natl Acad Sci U S A. David A. Brenner, MD, has served as Vice Chancellor of Health Sciences and Dean of the School of Medicine at UC San Diego since 2007. 2001 Aug; 21(3):437-51. 2019 Apr 07; 20(7). Medicina (Kaunas). Gastroenterology. 2000 Nov 01; 28(21):4306-16. Neurobiol Aging. 1997 May; 25(5):1128-35. ( 21 ):4306-16 for bone marrow-derived stem cells in liver fibrosis pathology david brenner ucsd wife TDP-43G298S transgenic mice Apr 290. Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and.... Are an abundant source of tumor necrosis factor-alpha inhibits albumin gene expression through stimulation of activator 1... Biology with arrayed combinatorial microenvironments for bone marrow-derived stem cells in liver fibrosis on the and! 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